Cycle development is a statistical method to define the amount of vaporised hydrogen peroxide and the duration of the decontamination process required for process success.
Range of services
- D-value estimation and D-value determination
- Worst case studies
- Determination of aeration time to optimise the decontamination cycle
- Temperature and humidity mappings and chemical indicator mappings
- Customer specific cycle optimization
With a qualified workforce and substantial experience in isolator designs, SKAN is also able to offer cycle development for third party barrier isolators with external decontamination systems.
Limited Spearman-Karber Method first applied by SKAN, recommended by the FDA 
 Sigwarth V., Moirandat C., Development and Quantification of H2O2 Decontamination Cycles. PDA Journal of Pharmaceutical Science and Technology. Vol. 54, No. 4, July/August 2000. pp. 286–304.